Nicolae Paulescue
In 1916, he succeeded in developing an aqueous pancreatic extract which, when injected into a diabetic dog, proved to have a normalizing effect on blood sugar levels. Shortly after completing the experiments, he was called to service in the Romanian army.[2] After World War I, he resumed his research.[3]
From 24 April to 23 June 1921, Paulescue published four papers at the Romanian Section of the Society of Biology in Paris:
The effect of the pancreatic extract injected into a diabetic animal by way of the blood.
The influence of the time elapsed from the intravenous pancreatic injection into a diabetic animal.
The effect of the pancreatic extract injected into a normal animal by way of the blood.
An extensive paper on this subject – "Research on the Role of the Pancreas in Food Assimilation" – was submitted by Paulescu on 22 June to the Archives Internationales de Physiologie in Liège, Belgium, and was published in the August 1921 issue of this journal.[4] The method used by Paulescu to prepare his pancreatic extract was similar to a procedure described by the American researcher Israel Kleiner in an article published in 1919 in the Journal of Biological Chemistry. Using his procedure, Kleiner had been able to demonstrate significant reductions in the concentration of blood and urinary glucose after intravenous injections of his extract. Paulescu then secured the patent rights for his method of manufacturing pancreine on 10 April 1922 (patent no. 6254) from the Romanian Ministry of Industry and Trade.
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Primary Interests:
- Aggression, Conflict, Peace
- Applied Social Psychology
- Attitudes and Beliefs
- Causal Attribution
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Nicolae Paulescue
422 Mult avenue
Johnston
Albania
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